Licensed North Carolina Real Estate Broker — Affiliated with G Brokerage

Sell Your Commercial Property in Winston-Salem, NC

Winston-Salem is in the midst of an economic reinvention. The Innovation Quarter — a 330-acre biomedical research and mixed-use district built on historic R.J. Reynolds Tobacco Company property — has attracted over $1 billion in investment and repositioned the city as a life sciences and healthcare destination. For commercial property owners, this transformation creates a market with two distinct dynamics: premium demand near the Innovation Quarter and medical campuses, and value-oriented investment opportunities in established industrial and retail corridors. Understanding which dynamic applies to your property is essential to pricing it correctly.

No upfront feesConfidential process$500K - $10M+ properties
2x
Dual Expertise
Business broker + CRE advisor. Most brokers only do one.
90
Day Avg. to Offer
Well-priced properties with strong financials attract fast offers.
$0
Upfront Cost
Success-based fees only. You pay nothing until your property sells.
Market Intelligence

Winston-Salem Commercial Real Estate Market

Winston-Salem's economic transformation from tobacco manufacturing to biomedical research and healthcare is reshaping its commercial real estate market in fundamental ways. The Innovation Quarter has attracted Wake Forest School of Medicine, Invacare, and dozens of biotech startups, creating demand for specialized lab, office, and flex space that didn't exist a decade ago. This transformation radiates outward: nearby retail benefits from Innovation Quarter foot traffic, and residential development in the surrounding West End and Industry Hill neighborhoods drives further commercial demand.

The healthcare sector dominates Winston-Salem's economy through Atrium Health Wake Forest Baptist and Novant Health, two major hospital systems whose combined employment and capital investment anchor medical office demand throughout the city. Properties near the medical center campuses along Hawthorne Road, Silas Creek Parkway, and Hanes Mall Boulevard see consistent occupancy. The industrial market along I-40 Business and US-421 serves a mix of advanced manufacturing, food processing (Krispy Kreme, HanesBrands legacy), and regional distribution tenants.

Winston-Salem offers a compelling value proposition for CRE investors: Innovation Quarter-adjacent properties are appreciating rapidly, healthcare-anchored assets provide income stability, and industrial properties along major corridors deliver strong yields. Compared to Charlotte (90 minutes southeast) or the Triangle, Winston-Salem's lower entry prices and higher cap rates attract investors seeking to build yield-oriented portfolios. Sellers who understand this positioning and present institutional-quality materials can capture competitive offers from both local and out-of-market buyers.

250,000+
Population
0.9% annually
Annual Growth
45000
Median Income
0.038
Unemployment
Major Employers: Atrium Health Wake Forest Baptist, Wake Forest University, Hanesbrands, Reynolds American, Inmar Intelligence
Economic Drivers: Healthcare & Biotech, Education, Innovation Quarter, Financial Services, Manufacturing
What's Selling

Top Property Types in Winston-Salem

01

Office & Biotech

Winston-Salem's life sciences ecosystem — anchored by the Innovation Quarter and Wake Forest School of Medicine — creates specialized demand for lab, research, and flex properties that few mid-size cities can match. Properties with appropriate power, HVAC, ventilation, and loading infrastructure suitable for biomedical tenants command significant premiums. The Innovation Quarter's success has also created spillover demand in adjacent neighborhoods, where adaptive reuse of older industrial buildings into creative office and lab space is accelerating.

02

Industrial / Warehouse

With Atrium Health Wake Forest Baptist and Novant Health both operating major hospital campuses in Winston-Salem, the city's medical office market is one of the most stable CRE asset classes in the Piedmont Triad. Properties along Hawthorne Road, near Hanes Mall, and on the Silas Creek medical corridor benefit from captive physician demand and patient traffic. Multi-specialty buildings with a mix of primary care, orthopedics, cardiology, and outpatient services generate the strongest investor interest.

03

Retail & Mixed-Use

I-40 Business, US-421, and the Kernersville-adjacent corridors give Winston-Salem's industrial market strong transportation connectivity. The city's manufacturing heritage — from textiles and tobacco to today's advanced manufacturing and food processing — provides a tenant base that values Winston-Salem's workforce, cost structure, and logistics access. HanesBrands, Krispy Kreme, and numerous mid-size manufacturers maintain operations here, creating consistent warehouse and distribution demand.

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Market Data

Winston-Salem Cap Rate Ranges

Property TypeTypical Cap Rate
Industrial6.5% - 8.5%
Retail7.0% - 9.5%
Office7.0% - 9.5%
Mixed-Use6.5% - 8.5%
NNN Lease5.0% - 7.0%

Cap rates in Winston-Salem are attractive relative to the Triangle, with improving fundamentals driven by Innovation Quarter growth and healthcare expansion.

Your Advisor

Why Winston-Salem Property Owners Work With John Salony

Dual Expertise

Most CRE agents don't understand business valuations. Most business brokers don't do real estate. John does both, giving you a complete picture of your property's value.

No Wasted Time

Pre-qualified buyers. Realistic pricing from day one. Clean financials and marketing materials that attract serious offers, not tire-kickers.

Confidential Process

Your tenants, employees, and competitors won't know you're selling until you're ready. Every step is managed with discretion.

Success-Based Fee

You pay nothing upfront. John's fee is earned only when your property sells. Your interests are fully aligned.

Common Questions

Selling Commercial Property in Winston-Salem

Office and biotech space near Innovation Quarter and medical office near Wake Forest Baptist are the strongest performers, along with downtown mixed-use properties benefiting from revitalization.
Most commercial property sales in Winston-Salem take 4 to 10 months from listing to closing. Innovation Quarter-adjacent and medical properties tend to move more quickly.
Winston-Salem cap rates vary significantly by asset class and proximity to growth drivers. Innovation Quarter-adjacent and medical campus properties trade tightest at 5.5% to 7.5%. Industrial along I-40 Business and US-421 ranges from 6.5% to 8.5%. Retail near Hanes Mall and Thalhimer trade at 6.5% to 9.0%. General office varies widely from 7.0% to 10.0%, with Innovation Quarter-influenced locations performing best. NNN properties with creditworthy tenants can trade below 5.5%.
Yes — Winston-Salem's healthcare and life sciences ecosystem creates particularly strong opportunities for combined business-and-real-estate transactions. Medical practices, laboratory services, and specialty clinics near the major hospital campuses are frequently acquired as combined deals. John Salony structures these transactions with options including sale-leaseback arrangements, allowing you to monetize the real estate while maintaining your practice location and patient relationships.
The Innovation Quarter continues attracting new tenants and investment, Wake Forest Baptist and Novant Health are both expanding, and industrial demand along the I-40 corridor remains strong. Winston-Salem's ongoing transformation from manufacturing to innovation and healthcare is creating appreciation opportunities that didn't exist five years ago, particularly for properties near the Innovation Quarter and medical campuses. Contact John Salony for a confidential assessment of your property's value in this evolving market.
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